AUTOIMMUNE
CASPR2 AB
LOWER LIMB ACTION MYOCLONUS
SEGMENTAL/ PROPRIOSPINAL MYOCLONUS
EPISODIC ATAXIA
NEUROMYOTONIA/ MYOKYMIA
SMALL CALL CARCINOMA LUNG
THYOMOMA
MRI: BASAL GANGLIA HYPERINTENSITY
GLYCINE RECEPTOR AB
HYPEREKPLEXIA
PERM:
LIMB OR AXIAL PAINFUL SPASMS
RIGIDITY/ NYSTAGUS/ OPSOCLONUS
CORTICAL MYOCLONUS/ STARTLE
DEAFNESS/ OPHTHALMOPARESIS
DYSARTHRIA
APNEA/ HYPERSOMNOLENCE
ASSOCIATED WITH THYMOMA
LAB: CSF PLEOCYTOSIS
LGI1 AB
FACIOBRACHIAL DYSTONIC SEIZURES
DROP/ ATONIC ATTACKS
HYPONATREMIA
EPISODIC BRADYCARDIA
IgLON5 AB
SLEEP PROBLEMS:
OSA/RBD/NREM/ STRIDOR
OCULAR:
SACCADIC INTRUSIONS/ VSGP
SYMPTOMS:
COGNITION/SEIZURES/ENCEPHALOPATHY
PARKINSONISM/DYSTONIA/ATAXIA
OROMANDIBULAR DYSTONIA
OROFACIAL DYSKINESIA
HYPEREKPLEXIA
MYORHYTHMIA/ TREMOR
AUTONOMIC DYSFUNCTION
DIABETES INSIPIDUS/ MYOKYMIA
PHENOTYPES
CBS/ PSP/MSA/HD/SPS/MND
DPPX6 AB
COGNITION
THORACIC STIFFNESS
PARKINSONISM (PSP PHENOTYPE)
BRAIN STEM INVOLVEMENT
GI DYSAUTONOMIA
DIARRHOEA/ WEIGHT LOSS
TREMOR/ MYOCLONUS/ HYPEREKPLEXIA
SEIZURES/ PARKINSONISM/ ATAXIA
GFAP AB
MENINGOENCEPHALOMYELITIS
ATAXIA (30%)
TREMORS(30%)
PSYCHIATRIC(30%)
AUTONOMIC (30%)
MRI: LINEAR PERIVENTRICAL CONTRAST ENHANCEMENT
GAD AB
PHENOTYPE
ATAXIA/ PARKINSONISM/ PSP
STIFF PERSON SYNDROME
STARTLE MYOCLONUS/ PERM
HEAD RETRACTION JERK
OPSOCLONUS-MYOCLONUS
ORTHOSTATIC TREMOR
LIMBIC ENCEPHALITIS/ MTLE
ABNORMAL SACCADES
VELOCITY/LATENCY/ACCURACY
SACCADE INITIATION/ EARLY UPGAZE PALSY
NYSTAGMUS
DOWN/ UP BEAT NYSTAGMUS
PERIODIC ALTERNATING NYSTAGMUS
FLUTTER/OPSOCLONUS/ STIFF EYES
>50YRS: 8%+VE GAD POSITIVE
OPSOMYOCLONUS ATAXIA
NEUROBLASTOMA
LAB: URINE VMA/ METANEPHRINE
RI AB
AGE OF ONSET >40YRS
SUBACUTE ONSET PARKINSONISM
JAW CLOSING DYSTONIA
PSP PHENOTYPE
OCULOPALATAL-MYOCLONUS
NEOPLASIA: BREAST/ OVARY
GAD AB
PHENOTYPE
ATAXIA/ PARKINSONISM/ PSP
STIFF PERSON SYNDROME
STARTLE MYOCLONUS/ PERM
HEAD RETRACTION JERK
OPSOCLONUS-MYOCLONUS
ORTHOSTATIC TREMOR
LIMBIC ENCEPHALITIS/ MTLE
ABNORMAL SACCADES
VELOCITY/LATENCY/ACCURACY
SACCADE INITIATION/ EARLY UPGAZE PALSY
NYSTAGMUS
DOWN/ UP BEAT NYSTAGMUS
PERIODIC ALTERNATING NYSTAGMUS
FLUTTER/OPSOCLONUS/ STIFF EYES
>50YRS: 8%+VE GAD POSITIVE
NMDA AB
MUTISM/ AUTONOMIC DYSFUNCTION
CENTRAL HYPOVENTILATION
STEREOTYPE (PRESENT IN SLEEP)
FACE DYSKINESIA
LIMB/TRUNK DYSKINESIA
PSYCHOSIS PRESENTATION
FEVER/ HEADACHE/ VOMITING
POST HSV/ VZV INFECTION
NEOPLASIA: OVARY/ BREAST
SMALL CELL LUNG CARCINOMA
GLYCINE-RECEPTOR AB
HYPEREKPLEXIA/ PERM
GABA-B RECEPTOR AB
SEIZURES/ MYORHYTHMIA
KELCH LIKE (KLH11 AB)
RHOMBENCEPHALITIS
DEAFNESS/VERTIGO
TESTICULAR SEMINOMA
BRAINSTEM/ MTL / DENTATE HYPERINTENSITY
POST-INFECTIOUS
IDIOPATHIC
PERM
GAD/ GLYCINE-RECEPTOR/ DPPX6 AB
LIMB OR AXIAL PAINFUL SPASMS
RIGIDITY/ NYSTAGUS/ OPSOCLONUS
CORTICAL MYOCLONUS/ STARTLE
DEAFNESS/ OPHTHALMOPARESIS
DYSARTHRIA
APNEA/ HYPERSOMNOLENCE
ASSOCIATED WITH THYMOMA
LAB: CSF PLEOCYTOSIS
CATAPLEXY
MA2 AB
CATAPLEXY
CASPR2 AB
LOWER LIMB ACTION MYOCLONUS
SEGMENTAL/ PROPRIOSPINAL MYOCLONUS
SMALL CALL CARCINOMA LUNG
THYMOMA
LGI1 AB
FACIOBRACHIAL DYSTONIC SEIZURES
DROP/ ATONIC ATTACKS
HYPONATREMIA
EPISODIC BRADYCARDIA
METABOLIC
DRUGS
ANTIPARKINSONISM
LEVODOPA
BROMOCRIPTINE
AMANTADINE
ANTIDEPRESSANTS
TCA
SSRI
LITHIUM
ANXIOLYTICS
BUSPIRONE
BENZODIAZEPINE WITHDRAWAL
DOPAMINE BLOCKING AGENTS
ANTIPSYCHOTIC DRUGS
METOCHLOPRAMIDE
ANTIEPILEPTICS
CARBAMAZEPINE
PHENYTOIN
GABAPENTINE
LAMOTRIGINE
DOPAMINE BLOCKING AGENTS
ANTIPSYCHOTIC DRUGS
METOCHLOPRAMIDE
OPIATE DRUGS
MORPHINE
FENTANYL
METHADONE
ANTI-NEOPLASTIC
CHLORAMBUCIL
IOFDAMIDE
ANTI-INFECTIVE
PENICILLIN
CEPHALOSPORINE
IMEPENEM
PIPERACILLIN
QUINOLONES
ISONIAZIDE
ACYCLOVIR
CARDIOVASCULAR
DILTIAZEM
NIFEDIPINE
GENERAL ANESTHETICS
PROPOFOL
ETOMIDATE
ENFLURANE
METABOLIC
RENAL FAILURE
LIVER FAILURE
HYPOXIA
THYROTOXICOSIS
HYPOGLYCAEMIA
NON-KETOTIC HYPERGLYCEMIA
HYPONATRAEMIA
HYPOCALCAEMIA
